The growth in the number of cancer cases has for a long time affected the contemporary society. There is, therefore, a need to find solutions to the problem, which is why researches and medical experts work constantly in collaboration to develop an effective way of dealing with cancer. Many healthcare organizations in US, UK and the rest of the world are working so hard to find more crucial information about cancer and understand the mechanism of the deadly disease better.
This article will tell you about a few recently found facts and news on cancer.
According to the results of a research held in August, 2016 at Michigan Technological University, scientists developed a procedure that could lead to better and stickier gene therapy drugs. The drugs will be made of strands of synthetic DNA, which are basically short and distinct. Better known as antisense DNA, the drugs are expected to work by stopping the growth of maladies like HIV/AIDS, Ebola and cancer by blocking body cells from making harmful proteins.
Two of the synthetic DNA drugs are already on the market. However, others are still in clinical trials.
Scientists at the Spanish National Cancer Research Centre conducted a research through which they discovered why cancer cells may be defiant to drugs premeditated to ‘starve’ tumors of nutrients and energy that allow them to grow and develop. The research was funded by the UK Charity Worldwide Cancer Research Organization and was published in a journal called Cancer Cell. It identified one of the most imperative biochemical mechanisms that enable cancer cells to survive even without energy supply (glucose). They also discovered a group of proteins which acts as a ‘switch’ to the process by detecting whether glucose is present or not.
According to the research, when glucose is available, cancer cells use one biochemical path to survive. But, when there is no food, the switch triggers another path so as to attain the same goal, allowing the cancer cells to continue to thrive. This is believed to be the main reason why tumors are resistant to most anti-angiogenic agents.
In another research, held at Rutgers Cancer Institute of New Jersey, scientists discovered a new and better approach to cutting off the cancer cell’s fuel supply. It works by targeting the autophagy (a cellular survival mechanism). This research was conducted because 85% to 90% of lung cancers are NSCLC (non-small-cell lung cancer), which have a typically poor response to standard treatment. The research is intended to make a great improvement to the fight against metastatic diseases if well combined with recently developed therapies that target some lung cancer mutations in the PI3K, MAPK and WGFR signaling pathways.